25/05/2018, 08:32
Assignments and solutions
Assignments cover the topics discussed in the corresponding lecture sessions VN-LEC# MIT-LEC # ASSIGNMENTs SOLUTIONS 3, 23, 29, 30, 32 1-5 Problem Set 1 (PDF) ...
| VN-LEC# | MIT-LEC # | ASSIGNMENTs | SOLUTIONS |
| 3, 23, 29, 30, 32 | 1-5 | Problem Set 1 (PDF) | (PDF) |
| 18, 27, 29, 30 | 6-9 | Problem Set 2 (PDF) | (PDF) |
| 16, 20-23 | 11-15 | Problem Set 3 (PDF) | (PDF) |
| 24, 25 | 16-19 | Problem Set 4 (PDF) | (PDF) |
| 25-28 | 20-24 | Problem Set 5 (PDF) | (PDF) |
| 33, 28 | 25-30 | Problem Set 6 (PDF) | (PDF) |
| 31 | 31-35 | Problem Set 7 (PDF) | (PDF) |
- A. is composed of amino acids
- B. is organized in the nucleus by histones
- C. is produced from RNA
- D. is present in 46 pairs in human cells
A chromosome:
D. is present in 46 pairs in human cells
- A. never function when they contain a mutation
- . directly produce proteins
- C. contain random pairings of nucleotides
- D. all of the above
- E. none of the above
Genes:
E. none of the above
- A. DNA to RNA
- B. RNA to DNA
- C. DNA to protein
- D. Protein to RNA
During the process of transcription, genetic information is transferred from:
A. DNA to RNA
- A. increases/protein
- B. decreases/mRNA
- C. decreases/ protein
- D. increases/mRNA
- E. all of the above
- F. none of the above
A mutation that __________ production of a given _________ can manifest as clinical disease.
F. none of the above
- A. clinical disease will develop based on the mutation alone.
- B. environmental factors can play a large role in the development of clinical disease.
- C. each person with the same mutation will follow the same clinical course.
- D. family members should be tested for this hereditary condition.
A mutation occurs that disrupts the normal structure and function of hemoglobin. Which of the following is true?
A. clinical disease will develop based on the mutation alone.
- A. is never passed from parents to offspring // is present in all cells of one’s body
- B. is always passed from parents to offspring // is present in all cells of one’s body
- C. is present in all cells of one’s body // is never passed from parents to offspring
- D. is responsible for non-hereditary cancers // is not often a direct cause of inherited disease
A germline mutation ___________ while a somatic mutation _______________.
C. is present in all cells of one’s body // is never passed from parents to offspring
- A. does not affect protein structure
- B. does not affect protein function
- C. leads to substitution of an amino acid in a new place in the protein
- D. all of the above
- E. none of the above
A missense mutation
C. leads to substitution of an amino acid in a new place in the protein
- A. does not affect protein structure
- B. may not lead to clinical disease
- C. involves an inappropriate stop codon
- D. A and B
- E. A and C
- F. All of the above
A nonsense mutation
C. involves an inappropriate stop codon
- A. results in no change in protein structure/function
- B. can sometimes lead to clinical disease
- C. involves substitution of one amino acid for another
- D. A and C
- E. A and B
A silent mutation
A. results in no change in protein structure/function
- True
- Flase
A polymorphism is a form of mutation that leads to clinical disease.
False
